Materials and Methods: The anticonvulsant and anxiolytic potential of APE (100-800 mg/kg) was evaluated against Pentylenetetrazole (PTZ), Bicuculline (BCL), Increasing current electroshock (ICES) and Elevated plus maze(EPM) models. Aim of the Study: To rationalize the ethnomedical claim and screen for anxiolytic and neurotoxicity profile of ethanolic extract of Aqarqarha (Anacyclus pyrethrum) root (APE). Baitar, “Al-Jam-e-ul-Mufradat-Al-Adviah-Wal-Aghziya (Urdu translation),” CCRUM publication, New Delhi, 1999.Īnticonvulsant, Anxiolytic and Neurotoxicity Profile of Aqarqarha (Anacyclus pyrethrum) DC (Compositae) Root Ethanolic ExtractĪUTHORS: Syed Mohd Abbas Zaidi, Shadab Ahmad Pathan, Surender Singh, Shakir Jamil, Farhan Jalees Ahmad, Roop Krishen KharĪqarqarha HPTLC Epilepsy Aqarqarha (Anacyclus pyrethrum)ĪBSTRACT: Ethnopharmacological relevance: Aqarqarha (Anacyclus pyrethrum) DC root has long been used as a traditional an-tiepileptic remedy in Unani system of medicine over centuries.
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